An easy access to two epimeric N-substituted (2S)-2-(2'-hydroxypropyl)pyrrolidines
نویسندگان
چکیده
منابع مشابه
An Easy Access to Two Epimeric N - Substituted ( 2 S ) - 2 - ( 2 ́ - Hydroxypropyl ) pyrrolidines
There are entries for the racemic alcohols 3 and 4, and also of enantiomerically pure 4. Our interest developed knowing the fact that pyrrolidine derivatives possess biological activities. For obtaining the aforementioned alcohols, our first approach was to prepare ketones 5a and 6 in the enantiomerically pure forms. In fact racemic 5 was prepared earlier in four steps by a tandem S N 2-Michael...
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ژورنال
عنوان ژورنال: Journal of the Brazilian Chemical Society
سال: 2005
ISSN: 0103-5053
DOI: 10.1590/s0103-50532005000600017